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Resolving deconvolution ambiguity in gene alternative splicing
BACKGROUND: For many gene structures it is impossible to resolve intensity data uniquely to establish abundances of splice variants. This was empirically noted by Wang et al. in which it was called a "degeneracy problem". The ambiguity results from an ill-posed problem where additional inf...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739860/ https://www.ncbi.nlm.nih.gov/pubmed/19653895 http://dx.doi.org/10.1186/1471-2105-10-237 |