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Down-Regulation of Platelet Surface CD47 Expression in Escherichia coli O157:H7 Infection-Induced Thrombocytopenia

BACKGROUND: Platelet depletion is a key feature of hemolytic uremic syndrome (HUS) caused by Shiga toxin-producing Escherichia coli (STEC) infection. The mechanism underlying STEC-induced platelet depletion, however, is not completely understood. METHODOLOGY/PRINCIPAL FINDINGS: Here we demonstrated...

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Detalles Bibliográficos
Autores principales: Guo, Ya-Lan, Liu, Dan-Qing, Bian, Zhen, Zhang, Chen-Yu, Zen, Ke
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2740826/
https://www.ncbi.nlm.nih.gov/pubmed/19771158
http://dx.doi.org/10.1371/journal.pone.0007131