Cargando…

NC2213: a novel methionine aminopeptidase 2 inhibitor in human colon cancer HT29 cells

Methionine aminopeptidase 2 (MetAP2) is a bifunctional protein that plays a critical role in the regulation of post-translational processing and protein synthesis. MetAP2 is overexpressed in human colon cancer. In this report we screened various MetAP2 inhibitors and treated HT29 cells with various...

Descripción completa

Detalles Bibliográficos
Autores principales: Selvakumar, Ponniah, Lakshmikuttyamma, Ashakumary, Das, Umashankar, Pati, Hari N, Dimmock, Jonathan R, Sharma, Rajendra K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2740849/
https://www.ncbi.nlm.nih.gov/pubmed/19703310
http://dx.doi.org/10.1186/1476-4598-8-65