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Both high intratumoral microvessel density determined using CD105 antibody and elevated plasma levels of CD105 in colorectal cancer patients correlate with poor prognosis

CD105 and its ligand transforming growth factor β (TGFβ) are modulators of angiogenesis, which drives tumour growth and metastasis. Tumour microvessel density (MVD) has proven to be an important determinant of prognosis. In this study, we have examined the prognostic value of MVD identified using Ma...

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Detalles Bibliográficos
Autores principales: Li, C, Gardy, R, Seon, B K, Duff, S E, Abdalla, S, Renehan, A, O'Dwyer, S T, Haboubi, N, Kumar, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741032/
https://www.ncbi.nlm.nih.gov/pubmed/12778073
http://dx.doi.org/10.1038/sj.bjc.6600874