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Antiangiogenic properties of selected ruthenium(III) complexes that are nitric oxide scavengers
The nitric oxide synthase (NOS) pathway has been clearly demonstrated to regulate angiogenesis. Increased levels of NO correlate with tumour growth and spreading in different experimental and human cancers. Drugs interfering with the NOS pathway may be useful in angiogenesis-dependent tumours. The a...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741040/ https://www.ncbi.nlm.nih.gov/pubmed/12778081 http://dx.doi.org/10.1038/sj.bjc.6600906 |