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Antiangiogenic properties of selected ruthenium(III) complexes that are nitric oxide scavengers

The nitric oxide synthase (NOS) pathway has been clearly demonstrated to regulate angiogenesis. Increased levels of NO correlate with tumour growth and spreading in different experimental and human cancers. Drugs interfering with the NOS pathway may be useful in angiogenesis-dependent tumours. The a...

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Detalles Bibliográficos
Autores principales: Morbidelli, L, Donnini, S, Filippi, S, Messori, L, Piccioli, F, Orioli, P, Sava, G, Ziche, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741040/
https://www.ncbi.nlm.nih.gov/pubmed/12778081
http://dx.doi.org/10.1038/sj.bjc.6600906