Gene therapy for bladder cancer using E1B-55 kD-deleted adenovirus in combination with adenoviral vector encoding plasminogen kringles 1–5

Mutations or loss of heterozygosity of p53 are detected in approximately 50% of bladder cancers. E1B-55 kD-deleted adenovirus has been shown to kill tumour cells with defective p53 function while sparing normal cells. Here, we examined the cytolytic effect and replication of E1B-55 kD-deleted adenov...

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Detalles Bibliográficos
Autores principales: Hsieh, J-L, Wu, C-L, Lai, M-D, Lee, C-H, Tsai, C-S, Shiau, A-L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741042/
https://www.ncbi.nlm.nih.gov/pubmed/12778082
http://dx.doi.org/10.1038/sj.bjc.6600908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741042/
https://www.ncbi.nlm.nih.gov/pubmed/12778082
http://dx.doi.org/10.1038/sj.bjc.6600908

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