Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3β (GSK-3β) in vitro

Cell adhesion to extracellular matrix (ECM) is thought to confer resistance against cell-damaging agents, that is, drugs and radiation, in tumour and normal cells in vitro. The dependence of cell survival on β1-integrin-linked kinase (ILK), protein kinase Bα/Akt (PKBα/Akt) and glycogen synthase kina...

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Detalles Bibliográficos
Autores principales: Cordes, N, van Beuningen, D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741045/
https://www.ncbi.nlm.nih.gov/pubmed/12778079
http://dx.doi.org/10.1038/sj.bjc.6600912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741045/
https://www.ncbi.nlm.nih.gov/pubmed/12778079
http://dx.doi.org/10.1038/sj.bjc.6600912

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