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Absence of BRAF gene mutations in uveal melanomas in contrast to cutaneous melanomas

The recent discovery of activating mutations in the BRAF gene in many cutaneous melanomas led us to screen the genomic sequence of BRAF exons 11 and 15 in a series of 48 intraocular (uveal) melanomas, together with control samples from three cutaneous melanomas and the SK-Mel-28 cell line, which has...

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Detalles Bibliográficos
Autores principales: Edmunds, S C, Cree, I A, Dí Nícolantonío, F, Hungerford, J L, Hurren, J S, Kelsell, D P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741050/
https://www.ncbi.nlm.nih.gov/pubmed/12778069
http://dx.doi.org/10.1038/sj.bjc.6600919