Linkage and association analysis of nevus density and the region containing the melanoma gene CDKN2A in UK twins

Rare mutations in the CDKN2A gene are highly penetrant for melanoma. Density of nevi is under strong genetic control and high density is a potent risk factor for melanoma. We used linkage and association analysis in adolescent twins from the UK to examine the hypothesis that the region containing th...

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Detalles Bibliográficos
Autores principales: Barrett, J H, Gaut, R, Wachsmuth, R, Bishop, J A Newton, Bishop, D T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741098/
https://www.ncbi.nlm.nih.gov/pubmed/12799637
http://dx.doi.org/10.1038/sj.bjc.6600904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741098/
https://www.ncbi.nlm.nih.gov/pubmed/12799637
http://dx.doi.org/10.1038/sj.bjc.6600904

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