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Linkage and association analysis of nevus density and the region containing the melanoma gene CDKN2A in UK twins
Rare mutations in the CDKN2A gene are highly penetrant for melanoma. Density of nevi is under strong genetic control and high density is a potent risk factor for melanoma. We used linkage and association analysis in adolescent twins from the UK to examine the hypothesis that the region containing th...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741098/ https://www.ncbi.nlm.nih.gov/pubmed/12799637 http://dx.doi.org/10.1038/sj.bjc.6600904 |