Increased expression of cyclin E is associated with an increased resistance to doxorubicin in rat fibroblasts

Cell cycle progression in eukaryotic cells is regulated by a family of cyclin-dependent kinases (CDKs). Cyclin E is a regulatory subunit of CDK2 and drives cells from G1 to S phase. Increased expression of cyclin E is a frequent event in human malignancies and has been associated with poor prognosis...

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Detalles Bibliográficos
Autores principales: Sgambato, A, Camerini, A, Pani, G, Cangiano, R, Faraglia, B, Bianchino, G, De Bari, B, Galeotti, T, Cittadini, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741105/
https://www.ncbi.nlm.nih.gov/pubmed/12799643
http://dx.doi.org/10.1038/sj.bjc.6600970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741105/
https://www.ncbi.nlm.nih.gov/pubmed/12799643
http://dx.doi.org/10.1038/sj.bjc.6600970

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