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Increased expression of cyclin E is associated with an increased resistance to doxorubicin in rat fibroblasts

Cell cycle progression in eukaryotic cells is regulated by a family of cyclin-dependent kinases (CDKs). Cyclin E is a regulatory subunit of CDK2 and drives cells from G1 to S phase. Increased expression of cyclin E is a frequent event in human malignancies and has been associated with poor prognosis...

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Detalles Bibliográficos
Autores principales:	Sgambato, A, Camerini, A, Pani, G, Cangiano, R, Faraglia, B, Bianchino, G, De Bari, B, Galeotti, T, Cittadini, A
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2003
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741105/ https://www.ncbi.nlm.nih.gov/pubmed/12799643 http://dx.doi.org/10.1038/sj.bjc.6600970

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