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Zoledronic acid induces antiproliferative and apoptotic effects in human pancreatic cancer cells in vitro

Bisphosphonates (BPs) are an emerging class of drugs mostly used in the palliative care of cancer patients. We investigated the in vitro activity of the most potent antiresorptive BP, zoledronic acid (ZOL), on the growth and survival of three human pancreatic cancer (PC) cell lines (BxPC-3, CFPAC-1...

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Detalles Bibliográficos
Autores principales: Tassone, P, Tagliaferri, P, Viscomi, C, Palmieri, C, Caraglia, M, D'Alessandro, A, Galea, E, Goel, A, Abbruzzese, A, Boland, C R, Venuta, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741108/
https://www.ncbi.nlm.nih.gov/pubmed/12799645
http://dx.doi.org/10.1038/sj.bjc.6600986