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Effect of antivascular endothelial growth factor treatment on the intratumoral uptake of CPT-11
Promising preclinical activity with agents blocking the function of vascular endothelial growth factor (VEGF) has been observed in various cancer types, especially with combination therapy. However, these drugs decrease microvessel density, and it is not known whether this reduced vessel density (VD...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741115/ https://www.ncbi.nlm.nih.gov/pubmed/12799646 http://dx.doi.org/10.1038/sj.bjc.6601005 |