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Rapid detection of allelic losses in brain tumours using microsatellite repeat markers and high-performance liquid chromatography
High-performance liquid chromatography (HPLC) is a recently introduced high-capacity automated method for detecting unknown mutations (denaturing HPLC) or for sizing DNA fragments under nondenaturing conditions. We have adapted the HPLC method for detection of loss of heterozygosity (LOH) and used g...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741124/ https://www.ncbi.nlm.nih.gov/pubmed/12799632 http://dx.doi.org/10.1038/sj.bjc.6601025 |