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Rapid detection of allelic losses in brain tumours using microsatellite repeat markers and high-performance liquid chromatography

High-performance liquid chromatography (HPLC) is a recently introduced high-capacity automated method for detecting unknown mutations (denaturing HPLC) or for sizing DNA fragments under nondenaturing conditions. We have adapted the HPLC method for detection of loss of heterozygosity (LOH) and used g...

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Detalles Bibliográficos
Autores principales: Chernova, O B, Barnett, G H, Cowell, J K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741124/
https://www.ncbi.nlm.nih.gov/pubmed/12799632
http://dx.doi.org/10.1038/sj.bjc.6601025