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Alternative-Splicing in the Exon-10 Region of GABA(A) Receptor β(2) Subunit Gene: Relationships between Novel Isoforms and Psychotic Disorders
BACKGROUND: Non-coding single nucleotide polymorphisms (SNPs) in GABRB2, the gene for β(2)-subunit of gamma-aminobutyric acid type A (GABA(A)) receptor, have been associated with schizophrenia (SCZ) and quantitatively correlated to mRNA expression and alternative splicing. METHODS AND FINDINGS: Expr...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741204/ https://www.ncbi.nlm.nih.gov/pubmed/19763268 http://dx.doi.org/10.1371/journal.pone.0006977 |