The drug-resistance to gefitinib in PTEN low expression cancer cells is reversed by irradiation in vitro

BACKGROUND: Despite of the recent success of EGFR inhibitory agents, the primary drug-resistant becomes a major challenge for EGFR inhibitor therapies. PTEN gene is an important positive regulatory factor for response to EGFR inhibitor therapy. Low-expression of PTEN is clearly one of the important...

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Detalles Bibliográficos
Autores principales: Zhuang, Hong-Qing, Wang, Jun, Yuan, Zhi-Yong, Zhao, Lu-Jun, Wang, Ping, Wang, Chang-Li
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741431/
https://www.ncbi.nlm.nih.gov/pubmed/19723324
http://dx.doi.org/10.1186/1756-9966-28-123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741431/
https://www.ncbi.nlm.nih.gov/pubmed/19723324
http://dx.doi.org/10.1186/1756-9966-28-123

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