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The drug-resistance to gefitinib in PTEN low expression cancer cells is reversed by irradiation in vitro
BACKGROUND: Despite of the recent success of EGFR inhibitory agents, the primary drug-resistant becomes a major challenge for EGFR inhibitor therapies. PTEN gene is an important positive regulatory factor for response to EGFR inhibitor therapy. Low-expression of PTEN is clearly one of the important...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741431/ https://www.ncbi.nlm.nih.gov/pubmed/19723324 http://dx.doi.org/10.1186/1756-9966-28-123 |