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Gene expression profiling in equine polysaccharide storage myopathy revealed inflammation, glycogenesis inhibition, hypoxia and mitochondrial dysfunctions

BACKGROUND: Several cases of myopathies have been observed in the horse Norman Cob breed. Muscle histology examinations revealed that some families suffer from a polysaccharide storage myopathy (PSSM). It is assumed that a gene expression signature related to PSSM should be observed at the transcrip...

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Detalles Bibliográficos
Autores principales: Barrey, Eric, Mucher, Elodie, Jeansoule, Nicolas, Larcher, Thibaut, Guigand, Lydie, Herszberg, Bérénice, Chaffaux, Stéphane, Guérin, Gérard, Mata, Xavier, Benech, Philippe, Canale, Marielle, Alibert, Olivier, Maltere, Péguy, Gidrol, Xavier
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741442/
https://www.ncbi.nlm.nih.gov/pubmed/19664222
http://dx.doi.org/10.1186/1746-6148-5-29