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Common polymorphisms within the NR4A3 locus, encoding the orphan nuclear receptor Nor-1, are associated with enhanced β-cell function in non-diabetic subjects

BACKGROUND: Neuron-derived orphan receptor (Nor) 1, nuclear receptor (Nur) 77, and nuclear receptor-related protein (Nurr) 1 constitute the NR4A family of orphan nuclear receptors which were recently found to modulate hepatic glucose production, insulin signalling in adipocytes, and oxidative metabo...

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Detalles Bibliográficos
Autores principales: Weyrich, Peter, Staiger, Harald, Stančáková, Alena, Schäfer, Silke A, Kirchhoff, Kerstin, Ullrich, Susanne, Ranta, Felicia, Gallwitz, Baptist, Stefan, Norbert, Machicao, Fausto, Kuusisto, Johanna, Laakso, Markku, Fritsche, Andreas, Häring, Hans-Ulrich
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741445/
https://www.ncbi.nlm.nih.gov/pubmed/19682370
http://dx.doi.org/10.1186/1471-2350-10-77