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Molecular analysis of Ku redox regulation

BACKGROUND: DNA double-strand breaks (DSBs) can occur in response to ionizing radiation (IR), radiomimetic agents and from endogenous DNA-damaging reactive oxygen metabolites. Unrepaired or improperly repaired DSBs are potentially the most lethal form of DNA damage and can result in chromosomal tran...

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Detalles Bibliográficos
Autores principales: Bennett, Sara M, Neher, Tracy M, Shatilla, Andrea, Turchi, John J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741464/
https://www.ncbi.nlm.nih.gov/pubmed/19715578
http://dx.doi.org/10.1186/1471-2199-10-86