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Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets

BACKGROUND: Human peripheral blood monocytes (Mo) consist of subsets distinguished by expression of CD16 (FCγRIII) and chemokine receptors. Classical CD16(- )Mo express CCR2 and migrate in response to CCL2, while a minor CD16(+ )Mo subset expresses CD16 and CX3CR1 and migrates into tissues expressin...

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Detalles Bibliográficos
Autores principales: Ancuta, Petronela, Liu, Kuang-Yu, Misra, Vikas, Wacleche, Vanessa Sue, Gosselin, Annie, Zhou, Xiaobo, Gabuzda, Dana
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741492/
https://www.ncbi.nlm.nih.gov/pubmed/19712453
http://dx.doi.org/10.1186/1471-2164-10-403