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Transgene-specific host responses in cutaneous gene therapy: the role of cells expressing the transgene
A major issue in long-term gene therapy is host immune responses to therapeutic cells when transgene encodes a potential antigen. The nature of these responses depends on several factors including the type of cell and tissue expressing the transgene. Keratinocytes and fibroblasts, which are known to...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741533/ https://www.ncbi.nlm.nih.gov/pubmed/19440226 http://dx.doi.org/10.1038/gt.2009.67 |