C/EBPα Expression is Partially Regulated by C/EBPβ in Response to DNA Damage and C/EBPα Deficient Fibroblasts Display an Impaired G(1) Checkpoint

We observed that C/EBPα is highly inducible in primary fibroblasts by DNA damaging agents that induce strand breaks, alkylate and crosslink DNA as well as those that produce bulky DNA lesions. Fibroblasts deficient in C/EBPα (C/EBPα(-/-)) display an impaired G(1) checkpoint as evidenced by inappropr...

Descripción completa

Detalles Bibliográficos
Autores principales: Ranjan, Rakesh, Thompson, Elizabeth A., Yoon, Kyungsil, Smart, Robert C.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741539/
https://www.ncbi.nlm.nih.gov/pubmed/19581927
http://dx.doi.org/10.1038/onc.2009.176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741539/
https://www.ncbi.nlm.nih.gov/pubmed/19581927
http://dx.doi.org/10.1038/onc.2009.176

Ejemplares similares