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Transcriptional Signature and Memory Retention of Human-Induced Pluripotent Stem Cells

Genetic reprogramming of somatic cells to a pluripotent state (induced pluripotent stem cells or iPSCs) by over-expression of specific genes has been accomplished using mouse and human cells. However, it is still unclear how similar human iPSCs are to human Embryonic Stem Cells (hESCs). Here, we des...

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Detalles Bibliográficos
Autores principales: Marchetto, Maria C. N., Yeo, Gene W., Kainohana, Osamu, Marsala, Martin, Gage, Fred H., Muotri, Alysson R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741600/
https://www.ncbi.nlm.nih.gov/pubmed/19763270
http://dx.doi.org/10.1371/journal.pone.0007076