Limited Neutralizing Antibody Specificities Drive Neutralization Escape in Early HIV-1 Subtype C Infection

We previously showed that HIV-1 subtype C viruses elicit potent but highly type-specific neutralizing antibodies (nAb) within the first year of infection. In order to determine the specificity and evolution of these autologous nAbs, we examined neutralization escape in four individuals whose respons...

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Detalles Bibliográficos
Autores principales: Moore, Penny L., Ranchobe, Nthabeleng, Lambson, Bronwen E., Gray, Elin S., Cave, Eleanor, Abrahams, Melissa-Rose, Bandawe, Gama, Mlisana, Koleka, Abdool Karim, Salim S., Williamson, Carolyn, Morris, Lynn
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742164/
https://www.ncbi.nlm.nih.gov/pubmed/19763271
http://dx.doi.org/10.1371/journal.ppat.1000598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742164/
https://www.ncbi.nlm.nih.gov/pubmed/19763271
http://dx.doi.org/10.1371/journal.ppat.1000598

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