TOR-mediated autophagy regulates cell death in Drosophila neurodegenerative disease

Target of rapamycin (TOR) signaling is a regulator of cell growth. TOR activity can also enhance cell death, and the TOR inhibitor rapamycin protects cells against proapoptotic stimuli. Autophagy, which can protect against cell death, is negatively regulated by TOR, and disruption of autophagy by mu...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Lao, Uyen, Edgar, Bruce A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742187/
https://www.ncbi.nlm.nih.gov/pubmed/19720874
http://dx.doi.org/10.1083/jcb.200904090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742187/
https://www.ncbi.nlm.nih.gov/pubmed/19720874
http://dx.doi.org/10.1083/jcb.200904090

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