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TOR-mediated autophagy regulates cell death in Drosophila neurodegenerative disease
Target of rapamycin (TOR) signaling is a regulator of cell growth. TOR activity can also enhance cell death, and the TOR inhibitor rapamycin protects cells against proapoptotic stimuli. Autophagy, which can protect against cell death, is negatively regulated by TOR, and disruption of autophagy by mu...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742187/ https://www.ncbi.nlm.nih.gov/pubmed/19720874 http://dx.doi.org/10.1083/jcb.200904090 |