Peripheral sensitisation of nociceptors via G-proteindependent potentiation of mechanotransduction currents

Mechanical stimuli impinging on the skin are converted into electrical signals by mechanically gated ion channels located at the peripheral nerve endings of dorsal root ganglion (DRG) neurons. Under inflammatory conditions sensory neurons are commonly sensitised to mechanical stimuli; a putative mec...

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Detalles Bibliográficos
Autores principales: Lechner, Stefan G, Lewin, Gary R
Formato: Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2009
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742277/
https://www.ncbi.nlm.nih.gov/pubmed/19505980
http://dx.doi.org/10.1113/jphysiol.2009.175059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742277/
https://www.ncbi.nlm.nih.gov/pubmed/19505980
http://dx.doi.org/10.1113/jphysiol.2009.175059

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