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Peripheral sensitisation of nociceptors via G-proteindependent potentiation of mechanotransduction currents
Mechanical stimuli impinging on the skin are converted into electrical signals by mechanically gated ion channels located at the peripheral nerve endings of dorsal root ganglion (DRG) neurons. Under inflammatory conditions sensory neurons are commonly sensitised to mechanical stimuli; a putative mec...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Science Inc
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742277/ https://www.ncbi.nlm.nih.gov/pubmed/19505980 http://dx.doi.org/10.1113/jphysiol.2009.175059 |