Epidermal Growth Factor Receptor Phosphorylation Sites Ser(991) and Tyr(998) Are Implicated in the Regulation of Receptor Endocytosis and Phosphorylations at Ser(1039) and Thr(1041)

Aberrant expression, activation, and down-regulation of the epidermal growth factor receptor (EGFR) have causal roles in many human cancers, and post-translational modifications including phosphorylation and ubiquitination and protein-protein interactions directly modulate EGFR function. Quantitativ...

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Detalles Bibliográficos
Autores principales: Tong, Jiefei, Taylor, Paul, Peterman, Scott M., Prakash, Amol, Moran, Michael F.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742444/
https://www.ncbi.nlm.nih.gov/pubmed/19531499
http://dx.doi.org/10.1074/mcp.M900148-MCP200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742444/
https://www.ncbi.nlm.nih.gov/pubmed/19531499
http://dx.doi.org/10.1074/mcp.M900148-MCP200

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