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Evidence for a Shared Nuclear Pore Complex Architecture That Is Conserved from the Last Common Eukaryotic Ancestor

The nuclear pore complex (NPC) is a macromolecular assembly embedded within the nuclear envelope that mediates bidirectional exchange of material between the nucleus and cytoplasm. Our recent work on the yeast NPC has revealed a simple modularity in its architecture and suggested a common evolutiona...

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Detalles Bibliográficos
Autores principales: DeGrasse, Jeffrey A., DuBois, Kelly N., Devos, Damien, Siegel, T. Nicolai, Sali, Andrej, Field, Mark C., Rout, Michael P., Chait, Brian T.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742445/
https://www.ncbi.nlm.nih.gov/pubmed/19525551
http://dx.doi.org/10.1074/mcp.M900038-MCP200