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ApoG2 induces cell cycle arrest of nasopharyngeal carcinoma cells by suppressing the c-Myc signaling pathway

BACKGROUND: apogossypolone (ApoG2) is a novel derivate of gossypol. We previously have reported that ApoG2 is a promising compound that kills nasopharyngeal carcinoma (NPC) cells by inhibiting the antiapoptotic function of Bcl-2 proteins. However, some researchers demonstrate that the antiproliferat...

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Detalles Bibliográficos
Autores principales: Hu, Zhe-Yu, Sun, Jian, Zhu, Xiao-Feng, Yang, Dajun, Zeng, Yi-Xin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742515/
https://www.ncbi.nlm.nih.gov/pubmed/19698176
http://dx.doi.org/10.1186/1479-5876-7-74