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Cis-urocanic acid suppresses UV-B-induced interleukin-6 and -8 secretion and cytotoxicity in human corneal and conjunctival epithelial cells in vitro

PURPOSE: Urocanic acid (UCA) is a major ultraviolet (UV)-absorbing endogenous chromophore in the epidermis and is also an efficacious immunosuppressant. The anti-inflammatory and cytoprotective effects of cis-UCA were studied in ocular surface cell cultures exposed to UV-B irradiation. METHODS: Huma...

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Detalles Bibliográficos
Autores principales: Viiri, J., Jauhonen, H.M., Kauppinen, A., Ryhänen, T., Paimela, T., Hyttinen, J., Sorri, I., Laihia, J.K., Leino, L., Kaarniranta, K.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742640/
https://www.ncbi.nlm.nih.gov/pubmed/19753313