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An in vitro screening cascade to identify neuroprotective antioxidants in ALS

Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease, characterized by progressive dysfunction and death of motor neurons. Although evidence for oxidative stress in ALS pathogenesis is well described, antioxidants have generally shown poor efficacy in animal models and hum...

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Detalles Bibliográficos
Autores principales: Barber, Siân C., Higginbottom, Adrian, Mead, Richard J., Barber, Stuart, Shaw, Pamela J.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742740/
https://www.ncbi.nlm.nih.gov/pubmed/19439221
http://dx.doi.org/10.1016/j.freeradbiomed.2009.01.019