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An in vitro screening cascade to identify neuroprotective antioxidants in ALS
Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease, characterized by progressive dysfunction and death of motor neurons. Although evidence for oxidative stress in ALS pathogenesis is well described, antioxidants have generally shown poor efficacy in animal models and hum...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742740/ https://www.ncbi.nlm.nih.gov/pubmed/19439221 http://dx.doi.org/10.1016/j.freeradbiomed.2009.01.019 |