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Digital RNA Allelotyping Reveals Tissue-specific and Allele-specific Gene Expression in Human

We developed a digital RNA allelotyping method for quantitatively interrogating allele-specific gene expression. This method involves ultra-deep sequencing of padlock captured SNPs from the transcriptome. We characterized four cell lines established from two human subjects in the Personal Genome Pro...

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Detalles Bibliográficos
Autores principales: Zhang, Kun, Li, Jin Billy, Gao, Yuan, Egli, Dieter, Xie, Bin, Deng, Jie, Li, Zhe, Lee, Je-Hyuk, Aach, John, Leproust, Emily, Eggan, Kevin, Church, George
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742772/
https://www.ncbi.nlm.nih.gov/pubmed/19620972
http://dx.doi.org/10.1038/nmeth.1357