Cargando…
Calcium Elevation in Mitochondria Is the Main Ca(2+) Requirement for Mitochondrial Permeability Transition Pore (mPTP) Opening
We have investigated in detail the role of intra-organelle Ca(2+) content during induction of apoptosis by the oxidant menadione while changing and monitoring the Ca(2+) load of endoplasmic reticulum (ER), mitochondria, and acidic organelles. Menadione causes production of reactive oxygen species, i...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742844/ https://www.ncbi.nlm.nih.gov/pubmed/19515844 http://dx.doi.org/10.1074/jbc.M109.025353 |