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RAD18 transmits DNA damage signaling to elicit homologous recombination repair

To maintain genome stability, cells respond to DNA damage by activating signaling pathways that govern cell cycle checkpoints and initiate DNA repair. Cell cycle checkpoint controls should somehow connect with DNA repair processes, however, exactly how such coordination occurs in vivo is largely unk...

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Detalles Bibliográficos
Autores principales: Huang, Jun, Huen, Michael S. Y., Kim, Hongtae, Yun Leung, Charles Chung, Glover, J N Mark, Yu, Xiaochun, Chen, Junjie
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743127/
https://www.ncbi.nlm.nih.gov/pubmed/19396164
http://dx.doi.org/10.1038/ncb1865