Ah receptor represses acute phase response gene expression without binding to its cognate response element

Repression of the NF-κB pathway has been extensively researched due to its pivotal role in inflammation. We investigated the potential of the aryl hydrocarbon receptor (AHR) to suppress NF-κB regulated gene expression, especially acute phase genes, such as serum amyloid A (Saa). Using AHR mutants, i...

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Detalles Bibliográficos
Autores principales: Patel, Rushang D., Murray, Iain A., Flaveny, Colin A., Kusnadi, Ann, Perdew, Gary H.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743259/
https://www.ncbi.nlm.nih.gov/pubmed/19333233
http://dx.doi.org/10.1038/labinvest.2009.24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743259/
https://www.ncbi.nlm.nih.gov/pubmed/19333233
http://dx.doi.org/10.1038/labinvest.2009.24

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