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NADPH Oxidase-4 Mediates Myofibroblast Activation and Fibrogenic Responses to Lung Injury

The NADPH oxidase (NOX) family of enzymes, which catalyze the reduction of O(2) to form reactive oxygen species (ROS), have increased in number during eukaryotic evolution1,2. Seven isoforms of the NOX gene family have been identified in mammals; however, specific roles of NOX enzymes in mammalian p...

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Detalles Bibliográficos
Autores principales: Hecker, Louise, Vittal, Ragini, Jones, Tamara, Jagirdar, Rajesh, Luckhardt, Tracy R., Horowitz, Jeffrey C., Pennathur, Subramaniam, Martinez, Fernando J., Thannickal, Victor J.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743335/
https://www.ncbi.nlm.nih.gov/pubmed/19701206
http://dx.doi.org/10.1038/nm.2005