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Gross genomic damage measured by DNA image cytometry independently predicts gastric cancer patient survival

BACKGROUND: DNA aneuploidy reflects gross genomic changes. It can be measured by flow cytometry (FCM-DNA) or image cytometry (ICM-DNA). In gastric cancer, the prevalence of DNA aneuploidy has been reported to range from 27 to 100%, with conflicting associations with clinicopathological variables. Th...

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Detalles Bibliográficos
Autores principales: Belien, J A M, Buffart, T E, Gill, A J, Broeckaert, M A M, Quirke, P, Meijer, G A, Grabsch, H I
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743350/
https://www.ncbi.nlm.nih.gov/pubmed/19738619
http://dx.doi.org/10.1038/sj.bjc.6605266