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Mactinin, a fragment of cytoskeletal α-actinin, is a novel inducer of heat shock protein (Hsp)-90 mediated monocyte activation

BACKGROUND: Monocytes, their progeny such as dendritic cells and osteoclasts and products including tumor necrosis factor (TNF)-α, interleukin (IL)-1α and IL-1β play important roles in cancer, inflammation, immune response and atherosclerosis. We previously showed that mactinin, a degradative fragme...

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Detalles Bibliográficos
Autores principales: Luikart, Sharon D, Panoskaltsis-Mortari, Angela, Hinkel, Timothy, Perri, Robert T, Gupta, Kalpna, Oegema, Theodore R, Gupta, Pankaj
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743639/
https://www.ncbi.nlm.nih.gov/pubmed/19715605
http://dx.doi.org/10.1186/1471-2121-10-60