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Rho iso-alpha acids from hops inhibit the GSK-3/NF-κB pathway and reduce inflammatory markers associated with bone and cartilage degradation

BACKGROUND: Rho iso-alpha acids (RIAA) from hops have been shown to have anti-inflammatory properties. To understand the mechanisms, we evaluated the effect of RIAA in cell signaling pathways and inflammatory markers using various in vitro models. We also investigated their therapeutic effect in mic...

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Detalles Bibliográficos
Autores principales: Konda, Veera Reddy, Desai, Anuradha, Darland, Gary, Bland, Jeffrey S, Tripp, Matthew L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743673/
https://www.ncbi.nlm.nih.gov/pubmed/19712471
http://dx.doi.org/10.1186/1476-9255-6-26