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Expression of cadherin 23 isoforms is not conserved: implications for a mouse model of Usher syndrome type 1D

PURPOSE: We compared cadherin 23 (Cdh23) mRNA and protein variants in the inner ear and retina of wild-type and mutant mice and primates to better understand the pleiotropic effects of Cdh23 mutations, and specifically to understand the absence of retinal degeneration in Cdh23 mutant mice. METHODS:...

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Detalles Bibliográficos
Autores principales: Lagziel, Ayala, Overlack, Nora, Bernstein, Steven L., Morell, Robert J., Wolfrum, Uwe, Friedman, Thomas B.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2009
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743805/
https://www.ncbi.nlm.nih.gov/pubmed/19756182