Genetic Variants of the α-Synuclein Gene SNCA Are Associated with Multiple System Atrophy

BACKGROUND: Multiple system atrophy (MSA) is a progressive neurodegenerative disorder characterized by parkinsonism, cerebellar ataxia and autonomic dysfunction. Pathogenic mechanisms remain obscure but the neuropathological hallmark is the presence of α-synuclein-immunoreactive glial cytoplasmic in...

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Detalles Bibliográficos
Autores principales: Al-Chalabi, Ammar, Dürr, Alexandra, Wood, Nicholas W., Parkinson, Michael H., Camuzat, Agnes, Hulot, Jean-Sébastien, Morrison, Karen E., Renton, Alan, Sussmuth, Sigurd D., Landwehrmeyer, Bernhard G., Ludolph, Albert, Agid, Yves, Brice, Alexis, Leigh, P. Nigel, Bensimon, Gilbert
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743996/
https://www.ncbi.nlm.nih.gov/pubmed/19771175
http://dx.doi.org/10.1371/journal.pone.0007114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743996/
https://www.ncbi.nlm.nih.gov/pubmed/19771175
http://dx.doi.org/10.1371/journal.pone.0007114

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