Runx1 is required for the endothelial to hematopoietic cell transition but not thereafter

HSCs are the founder cells of the adult hematopoietic system, and thus knowledge of the molecular program directing their generation during development is important for regenerative hematopoietic strategies. Runx1 is a pivotal transcription factor required for HSC generation in the vascular regions...

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Detalles Bibliográficos
Autores principales: Chen, Michael J., Yokomizo, Tomomasa, Zeigler, Brandon, Dzierzak, Elaine, Speck, Nancy A.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744041/
https://www.ncbi.nlm.nih.gov/pubmed/19129762
http://dx.doi.org/10.1038/nature07619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744041/
https://www.ncbi.nlm.nih.gov/pubmed/19129762
http://dx.doi.org/10.1038/nature07619

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