THE HSP82 MOLECULAR CHAPERONE CAN PROMOTE A SWITCH BETWEEN UNEXTENDABLE AND EXTENDABLE TELOMERE STATES

Distinct protein assemblies are nucleated at telomeric DNA to both guard the ends from damage and lengthen the DNA following replication. In yeast, Cdc13 recruits either Stn1/Ten1 to form a protective cap or the telomerase holoenzyme to extend the DNA. We have established an in vitro yeast telomere...

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Detalles Bibliográficos
Autores principales: DeZwaan, Diane C., Toogun, Oyetunji A., Echtenkamp, Frank J., Freeman, Brian C.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744139/
https://www.ncbi.nlm.nih.gov/pubmed/19525972
http://dx.doi.org/10.1038/nsmb.1616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744139/
https://www.ncbi.nlm.nih.gov/pubmed/19525972
http://dx.doi.org/10.1038/nsmb.1616

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