VEGFR1 Activity Modulates Myeloid Cell Infiltration in Growing Lung Metastases but Is Not Required for Spontaneous Metastasis Formation

The role of vascular endothelial growth factor receptor 1 (VEGFR1/Flt1) in tumor metastasis remains incompletely characterized. Recent reports suggested that blocking VEGFR1 activity or the interaction with its ligands (VEGF and PlGF) has anti-tumor effects. Moreover, several studies showed that VEG...

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Detalles Bibliográficos
Autores principales: Dawson, Michelle R., Duda, Dan G., Chae, Sung-Suk, Fukumura, Dai, Jain, Rakesh K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744279/
https://www.ncbi.nlm.nih.gov/pubmed/19763275
http://dx.doi.org/10.1371/journal.pone.0006525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744279/
https://www.ncbi.nlm.nih.gov/pubmed/19763275
http://dx.doi.org/10.1371/journal.pone.0006525

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