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Avid interactions underlie the K63-linked polyubiquitin binding specificities observed for UBA domains

Ubiquitin (Ub) receptor proteins as a group must contain a diverse set of binding specificities to distinguish the many forms of polyUb signals. Previous studies suggested that the large class of ubiquitin associated (UBA) domains contains members with intrinsic specificity for lysine 63-linked poly...

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Detalles Bibliográficos
Autores principales: Sims, Joshua J., Haririnia, Aydin, Dickinson, Bryan C., Fushman, David, Cohen, Robert E.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744598/
https://www.ncbi.nlm.nih.gov/pubmed/19620964
http://dx.doi.org/10.1038/nsmb.1637